Decapeptide-12: Studies in Skin Cell Lightening and Anti-Aging
Decapeptide-12 is research peptide made of ten amino acids with the sequence YRSRKYSSWY, which appears to be a targeted inhibitor of melanogenesis that acts primarily by competitively blocking tyrosinase, the rate-limiting enzyme in melanin biosynthesis. The peptide...
ABP-7 Peptide Support for Cellular Signaling and Migration
ABP-7, also referred to as actin-binding peptide-7 or the TB-500 fragment, is a molecule made of seven amino acids that has the sequence of Acetyl-LKKTETQ. It appears to be a fragment of the 43-amino acid structure of the endogenously occurring Thymosin Beta 4...
B7-33 Potential Actions on Inflammation and Fibrosis
B7-33 is an experimental peptide designed as a simplified analogue of the natural hormone relaxin-2 (H2 relaxin). In physiological systems, relaxin family peptides such as H1, H2, and H3 relaxins, as well as several insulin-like peptides (INSL3–6) are thought to...
ACE-031 Actions on Muscle Cells, Bone Cells, and Fat Cells
ACE-031 is a complex protein structure consisting of a receptor and an antibody. It appears to act as a soluble decoy version of the activin receptor type IIB (ActRIIB), as the receptor is linked to an IgG1 Fc domain. The result is an ActRIIB IgG1 Fc fusion protein...
AHK-Cu and Hair Follicle Cell Cultures
AHK-Cu is classified as a tripeptide with the sequence of alanine–histidine–lysine (AHK) which has a copper ion attached to the middle amino acid - histidine. The AHK structure appears to have significant affinity to copper ions (Cu²⁺), mainly due to the imidazole...
Adipotide (FTPP) Actions on Fat Cell Size and Metabolism
Adipotide (FTPP) is considered to be a chimeric peptide (GKGGRAKDC-GG-D(KLAKLAK)2) engineered to target endothelial cells from white-adipose vasculature and induce their apoptosis. As a chimeric peptide, it is believed to consist of two functional parts. The first of...
The Neuroprotective and Gastroprotective Potential of Semax
Semax is a synthetic heptapeptide (Met–Glu–His–Phe–Pro–Gly–Pro) originally derived from fragments of adrenocorticotropic hormone (ACTH) but lacking hormonal activity. It consists of a 4-amino acid fragment (Met-Glu-His-Phe), which is a common part in the sequence of...
P021 Peptide: Neuroprotective and Neurotrophic Potential
P021 appears to be a short synthetic peptide that emerged from efforts to identify minimal structural elements of ciliary neurotrophic factor (CNTF) that retain activity while avoiding some of the limitations of the full protein, such as its antigenic potential. The...
Selank Peptide: Potential Support for Neurotransmitters and Neurotrophins
Selank is a synthetic heptapeptide, and the seven amino acids in its structure are in the configuration of Thr-Lys-Pro-Arg-Pro-Gly-Pro (TKPRPGP). The peptide appears to be a modified analogue of the endogenously occurring tetrapeptide Tuftsin (TKPR). However, Selank...