ACE-031 Actions on Muscle Cells, Bone Cells, and Fat Cells

ACE-031 Actions on Muscle Cells, Bone Cells, and Fat Cells

ACE-031 is a complex protein structure consisting of a receptor and an antibody. It appears to act as a soluble decoy version of the activin receptor type IIB (ActRIIB), as the receptor is linked to an IgG1 Fc domain. The result is an ActRIIB IgG1 Fc fusion protein...
AHK-Cu and Hair Follicle Cell Cultures

AHK-Cu and Hair Follicle Cell Cultures

AHK-Cu is classified as a tripeptide with the sequence of alanine–histidine–lysine (AHK) which has a copper ion attached to the middle amino acid – histidine. The AHK structure appears to have significant affinity to copper ions (Cu²⁺), mainly due to the...
Adipotide (FTPP) Actions on Fat Cell Size and Metabolism

Adipotide (FTPP) Actions on Fat Cell Size and Metabolism

Adipotide (FTPP) is considered to be a chimeric peptide (GKGGRAKDC-GG-D(KLAKLAK)2) engineered to target endothelial cells from white-adipose vasculature and induce their apoptosis. As a chimeric peptide, it is believed to consist of two functional parts. The first of...
The Neuroprotective and Gastroprotective Potential of Semax

The Neuroprotective and Gastroprotective Potential of Semax

Semax is a synthetic heptapeptide (Met–Glu–His–Phe–Pro–Gly–Pro) originally derived from fragments of adrenocorticotropic hormone (ACTH) but lacking hormonal activity. It consists of a 4-amino acid fragment (Met-Glu-His-Phe), which is a common part in the sequence of...
P021 Peptide: Neuroprotective and Neurotrophic Potential

P021 Peptide: Neuroprotective and Neurotrophic Potential

P021 appears to be a short synthetic peptide that emerged from efforts to identify minimal structural elements of ciliary neurotrophic factor (CNTF) that retain activity while avoiding some of the limitations of the full protein, such as its antigenic potential. The...
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