ACE-031 is a complex protein structure consisting of a receptor and an antibody. It appears to act as a soluble decoy version of the activin receptor type IIB (ActRIIB), as the receptor is linked to an IgG1 Fc domain. The result is an ActRIIB IgG1 Fc fusion protein...
AHK-Cu is classified as a tripeptide with the sequence of alanine–histidine–lysine (AHK) which has a copper ion attached to the middle amino acid – histidine. The AHK structure appears to have significant affinity to copper ions (Cu²⁺), mainly due to the...
Adipotide (FTPP) is considered to be a chimeric peptide (GKGGRAKDC-GG-D(KLAKLAK)2) engineered to target endothelial cells from white-adipose vasculature and induce their apoptosis. As a chimeric peptide, it is believed to consist of two functional parts. The first of...
Semax is a synthetic heptapeptide (Met–Glu–His–Phe–Pro–Gly–Pro) originally derived from fragments of adrenocorticotropic hormone (ACTH) but lacking hormonal activity. It consists of a 4-amino acid fragment (Met-Glu-His-Phe), which is a common part in the sequence of...
P021 appears to be a short synthetic peptide that emerged from efforts to identify minimal structural elements of ciliary neurotrophic factor (CNTF) that retain activity while avoiding some of the limitations of the full protein, such as its antigenic potential. The...
Selank is a synthetic heptapeptide, and the seven amino acids in its structure are in the configuration of Thr-Lys-Pro-Arg-Pro-Gly-Pro (TKPRPGP). The peptide appears to be a modified analogue of the endogenously occurring tetrapeptide Tuftsin (TKPR). However, Selank...