Melanotan II Interactions with Melanocortin Receptors
Melanotan II is a synthetic analog of the naturally occurring 13 amino acids of the alpha-melanocyte-stimulating hormone (α-MSH). While the peptide is based on α-MSH, it has important structural distinctions. Specifically, Melanotan II appears to be a cyclic peptide...
Examorelin (Hexarelin): Interactions With Neuroendocrine Signaling
Examorelin, also referred to as Hexarelin, P-23905, and MF-6003, is a research peptide that belongs to the group of growth hormone secretagogues (GHSs). That is because it works by activating the growth hormone secretagogue receptors 1a (GHSR1a) found in various nerve...
Emideltide (DSIP) Interactions with CNS Neurotransmitters
Emideltide, or Delta Sleep-Inducing Peptide (DSIP), is an endogenous peptide with nine amino acids. In relevant studies, the peptide was initially isolated from the central nervous system (CNS) of research models undergoing electrically induced sleep in laboratory...
Potential Synergistic Actions with Mod GRF (1-29) & GHRP-6 Blend
Modified Growth Hormone Releasing Factor (Mod GRF (1-29)) and Growth Hormone Releasing Peptide-6 (GHRP-6) are research peptides that may interact with different receptors on pituitary cells and possibly trigger the production of growth hormone (hGH). It is thought...
MT-1 (Melanotan 1) Impacts on Dermal, Brain, and Liver Cells
MT-1 (Melanotan 1) is considered to be a synthetic peptide structurally similar to the naturally occurring alpha-melanocyte-stimulating hormone (α-MSH), differing by two amino acid substitutions (methionine replaced by norleucine and L-phenylalanine replaced by...
Mechano Growth Factor (MGF) Peptide Actions on Muscular Tissue, Bone and Cartilage Cells
Mechano Growth Factor is a 24‐amino acid peptide derived from an alternatively spliced isoform of IGF‐1 (an anabolic mediator of growth hormone), specifically the IGF-IEc variant.(1) Scientists propose proteolytic processing of this isoform to yield both the mature...
Palmitoyl AHK Potential Actions on Hair and Dermal Cell Proliferation and Survival
Palmitoyl AHK appears to be a palmitoylated derivative of a short tripeptide, AHK, which is composed of alanine, histidine, and lysine.(1) Preliminary data collected in laboratory settings findings suggest that AHK may be involved in several cellular processes within...
Receptor Grade IGF-1 LR3 Peptide and Cellular Anabolism
Receptor Grade IGF-1 LR3 peptide may be described as a modified version of the endogenously occurring insulin-like growth factor 1 (IGF-1) - the endogenous mediator of the anabolic potential of growth hormone (hGH). In order to produce IGF-1 LR3, scientists sought to...
Protirelin (Thyrotropin TRH) and Brain Cell Signaling
Protirelin is a synthetic tripeptide (L-pyroglutamyl-L-h histidyl-L-proline amide) that has been developed as an analogue of a small peptide endogenously produced in hypothalamic cells called thyrotropin-releasing hormone (TRH).(1) It is thought that Protirelin may...