Sermorelin peptide (also sometimes known as GRF 1-29) is an analogue of the growth hormone releasing hormone. It is the shortest chain of functional amino acids, with 29 linked acids, making it a very common substance for growth research, and allowing researchers to investigate the occurrence of growth in varying exposures.
More specifically, this polypeptide is the acetate salt of an amidated synthetic compound, corresponding to the amino terminal section of the GHRH. Because this peptide is so easily synthesized, there is a great amount of potentially educational knowledge and understanding that can come from studying Sermorelin, including potential uses for this substance in the future.
What Is Sermorelin Used For?
Although study results have presented positive effects from Sermorelin peptide, it is still used primarily for research purposes, and there is still plenty to learn about this fascinating substance. The following will cover what this peptide does and how it works, as well as what has been uncovered about both its benefits and its side effects.
What Does Sermorelin Do?
Due to its ability to increase the natural levels of growth hormone in test subjects via the stimulation of the pituitary glands, Sermorelin has provided subjects the ability to initiate growth once again – even after their time for natural growth has ended.
Both individual cells and subjects that were exposed to this peptide in lab settings have presented significant levels of growth. The most effective results were presented when researchers administered the substance daily.
Sermorelin Half-life
Though more studies need to be done, post-exposure toxicity from Sermorelin within the subjects has not been evident. Regarding its duration, the half-life of Sermorelin peptide is quite short-lived – just about 12 minutes or so – but the subjects feel its effects very quickly.
How Does Sermorelin Work?
By exciting the pituitary gland, Sermorelin is able to increase the body’s natural growth hormone levels in the test subjects. This is done through a process wherein the peptide itself binds to the GHRH receptor and imitates the local growth hormone-releasing factor (GRF), because of its ability to promote growth hormone secretion in subjects.
To explain in more depth, the elevated concentration of human growth hormone (HGH) secreted by the pituitary gland leads to an increase in the liver’s formation of Insulin-Like Growth Factor 1, producing the advantageous perks offered by this peptide.
Since the pituitary gland’s secretion and body’s concentration of human growth hormone is already increased, the subject’s endocrine system will not permit the further production of growth hormone than can be safely processed by the body, thanks to the endocrine self-monitoring system.
Sermorelin Benefits
Because of the way Sermorelin works in the body, the blood stream’s elevated levels of IGF-1 leads to new cell growth within the bones and organs of the subjects’ body, as well as an increase in their metabolism.
Besides that, researchers have also pointed out that Sermorelin is more beneficial for application in age management and treatment – as opposed to the recombinant human growth hormone (rhGH). This is because Sermorelin does not lead to the excessive elevation of circulating human growth hormone, and to greatly contain somatotroph function by means of decline from disuse, it does not promote or speed up the aging effects.
That’s not all it offers.
List of Benefits
Research results of Sermorelin peptide have also indicated the following benefits:
- Increase in lean muscle mass
- Reduction of body fat
- Increase in bone density
- Enhancement of the immune system
- Increase in heart strength
- Increase in the strength of various other organs in the body
- Improvement in cognitive performance
- Improvement in body composition
- Increase in hair and nail growth
- Increase in sleep quality
- Reduction in the risk for diseases such as heart disease, diabetes, stroke, and more
- Enhancement in skin tone
- Increase in the overall quality of life
It must be stated, though, that the start and development of Sermorelin-induced perks are not as fast as those of rhGH. This is because there are additional steps in the process when the peptide is administered and used to produce these effects.
Sermorelin Side Effects
The more common side effects of this peptide include swelling, redness, or pain at the injection site. Some of the less occurring side effects include the following:
- Trouble swallowing
- Itching
- Flushing
- Dizziness
- Headache
- Trouble sitting still
- Drowsiness
Where to Buy Sermorelin
You can buy Sermorelin and other high quality peptides for research by checking out Core Peptides.
NOTE: The information found on this website and within this article is intended for educational or informational purposes only. Some or all of the content in these articles are not substantiated by a medical professional and may be based on the opinions of the writer who may not be a medical or accredited professional. Not intended for personal or human use. Please review our Terms and Conditions before purchasing.
Dr. Marinov (MD, Ph.D.) is a researcher and chief assistant professor in Preventative Medicine & Public Health. Prior to his professorship, Dr. Marinov practiced preventative, evidence-based medicine with an emphasis on Nutrition and Dietetics. He is widely published in international peer-reviewed scientific journals and specializes in peptide therapy research.